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Klotho in the cerebrospinal fluid of adults with and without Alzheimer's disease

The aging-suppressor gene klotho encodes a single-pass transmembrane protein that is predominantly secreted by the choroid plexus of the brain and in the kidney. Klotho-deficient mice develop multiple aging phenotypes, including impaired cognition. Klotho concentrations have not been described in th...

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Detalhes bibliográficos
Main Authors: Semba, Richard D., Moghekar, Abhay R., Hu, Jason, Sun, Kai, Turner, Randi, Ferrucci, Luigi, O'Brien, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037850/
https://ncbi.nlm.nih.gov/pubmed/24211693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2013.10.058
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