Rac1 as a potential therapeutic target for chemo-radioresistant head and neck squamous cell carcinomas (HNSCC)

BACKGROUND: In order to improve therapy for HNSCC patients, novel methods to predict and combat local and/or distant tumour relapses are urgently needed. This study has been dedicated to the hypothesis that Rac1, a Rho GTPase, is implicated in HNSCC insensitivity to chemo-radiotherapy resulting in t...

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Détails bibliographiques
Auteurs principaux: Skvortsov, S, Dudás, J, Eichberger, P, Witsch-Baumgartner, M, Loeffler-Ragg, J, Pritz, C, Schartinger, V H, Maier, H, Hall, J, Debbage, P, Riechelmann, H, Lukas, P, Skvortsova, I
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2014
Sujets:
Translational Therapeutics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037830/
https://ncbi.nlm.nih.gov/pubmed/24786604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.221
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