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A Population Threshold for Functional Polymorphisms
We sequenced 114 genes (for DNA repair, cell cycle arrest, apoptosis, and detoxification)in a mixed human population and observed a sudden increase in the number of functional polymorphisms below a minor allele frequency of ∼6%. Functionality is assessed by considering the ratio in the number of non...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC403778/ https://ncbi.nlm.nih.gov/pubmed/12902381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1324303 |
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