Changes in Vitamin D-Related Mineral Metabolism After Induction With Anti-Tumor Necrosis Factor-α Therapy in Crohn's Disease

CONTEXT: Preclinical studies suggest that TNF-α suppresses PTH synthesis, inhibits renal 1α-hydroxylase activity, and impairs fibroblast growth factor 23 (FGF23) degradation. The impact of inflammation on vitamin D and mineral metabolism has not been well-characterized in Crohn's disease (CD)....

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Main Authors: Augustine, Marianne V., Leonard, Mary B., Thayu, Meena, Baldassano, Robert N., de Boer, Ian H., Shults, Justine, Denson, Lee A., DeBoer, Mark D., Herskovitz, Rita, Denburg, Michelle R.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
Hot Topics in Translational Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037735/
https://ncbi.nlm.nih.gov/pubmed/24617709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-3846
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