Iron-chelating and anti-lipid peroxidation properties of 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one (CM1) in long-term iron loading β-thalassemic mice

OBJECTIVE: To evaluate the iron-chelating properties and free-radical scavenging activities of 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one (CM1) treatment in chronic iron-loaded β-thalassemic (BKO) mice. METHODS: The BKO mice were fed with a ferrocene-rich diet and were orally administ...

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Autors principals: Kulprachakarn, Kanokwan, Chansiw, Nittaya, Pangjit, Kanjana, Phisalaphong, Chada, Fucharoen, Suthat, Hider, Robert C., Santitherakul, Sineenart, Srichairatanakool, Somdet
Format: Artigo
Idioma:Inglês
Publicat: Asian Pacific Tropical Medicine Press 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037662/
https://ncbi.nlm.nih.gov/pubmed/25183338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12980/APJTB.4.2014APJTB-2014-0155
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