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Toxicity effects of water extracts of Holothuria atra Jaeger in mice

OBJECTIVE: To determine lethal median dose (LD(50)) and histopathological toxicity of water extract of Holothuria atra (H. atra) in mice. METHODS: The behavioral changes, mortality and histopathology examination on liver were assessed in mice 14 d after the administration (i.p.) of H. atra water ext...

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Detalhes bibliográficos
Main Authors: Hashim, Ridzwan Bin, Azizan, Nurul Alia, Zamli, Zaitunnatakin, Zulkipli, Farah Hanis, Mazlan, Nurzafirah, Althunibat, Osama Yousef
Formato: Artigo
Idioma:Inglês
Publicado em: Asian Pacific Tropical Medicine Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037654/
https://ncbi.nlm.nih.gov/pubmed/25183330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12980/APJTB.4.201414B154
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