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Properdin has an ascendancy over factor H regulation in complement-mediated renal tubular damage

BACKGROUND: Urinary (U)-complement components have been detected in patients with proteinuric renal diseases, and complement activation via the alternative pathway (AP) is believed to play a role in renal tubular damage. The present study aimed to examine the regulation of complement AP activation i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nagamachi, Seiji, Ohsawa, Isao, Suzuki, Hiyori, Sato, Nobuyuki, Inoshita, Hiroyuki, Hisada, Atsuko, Honda, Daisuke, Shimamoto, Mamiko, Shimizu, Yoshio, Horikoshi, Satoshi, Tomino, Yasuhiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037424/
https://ncbi.nlm.nih.gov/pubmed/24885016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-15-82
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