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Controlled Release and Gradient Formation of Human Glial-Cell Derived Neurotrophic Factor from Heparinated Poly(ethylene glycol) Microsphere-based Scaffolds

Introduction of spatial patterning of proteins, while retaining activity and releasability, is critical for the field of regenerative medicine. Reversible binding to heparin, which many biological molecules exhibit, is one potential pathway to achieving this goal. We have covalently bound heparin to...

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Detalhes bibliográficos
Main Authors: Roam, Jacob L., Nguyen, Peter K., Elbert, Donald L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037386/
https://ncbi.nlm.nih.gov/pubmed/24816282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.04.027
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