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Strikingly poor CD8(+) T cell immunogenicity of vaccinia virus strain MVA in BALB/c mice

Vaccinia virus (VACV) strain MVA is a highly attenuated vector for vaccines that is being explored in clinical trials. We compared the CD8(+) T cell immunogenicity of MVA with that of a virulent laboratory strain of VACV (strain WR) in BALB/c mice by examining epitope-specific responses as well as e...

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Detalhes bibliográficos
Main Authors: Russell, Tiffany A., Tscharke, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037371/
https://ncbi.nlm.nih.gov/pubmed/24566805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2014.10
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