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Low-dose 6-bromoindirubin-3′-oxime induces partial dedifferentiation of endothelial cells to promote increased neovascularization() (R1)

Endothelial cell (EC) dedifferentiation in relation to neovascularization is a poorly understood process. In this report we addressed the role of Wnt signaling in the mechanisms of neovascularization in adult tissues. Here, we show that a low-dose of 6-bromoindirubin-3′-oxime (BIO), a competitive in...

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Detalhes bibliográficos
Main Authors: KOHLER, ERIN E., BARUAH, JUGAJYOTI, URAO, NORIFUMI, USHIO-FUKAI, MASUKO, FUKAI, TOHRU, CHATTERJEE, ISHITA, WARY, KISHORE K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037358/
https://ncbi.nlm.nih.gov/pubmed/24496925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1658
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