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It takes two to tango, a dance between the cells of origin and cancer stem cells in the Drosophila larval brain

During malignant transformation the cells of origin give rise to cancer stem cells which possess the capacity to undergo limitless rounds of self-renewing division, regenerating themselves while producing more tumor cells. Within normal tissues, a limitless self-renewal capacity is unique to the ste...

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Detalhes bibliográficos
Main Authors: Janssens, Derek H., Lee, Cheng-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037343/
https://ncbi.nlm.nih.gov/pubmed/24631354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2014.03.006
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