Modeling human retinal development with patient-specific iPS cells reveals multiple roles for VSX2

Human induced pluripotent stem cells (hiPSCs) have been shown to differentiate along the retinal lineage in a manner that mimics normal mammalian development. Under certain culture conditions hiPSCs form optic vesicle-like structures (OVs), which contain proliferating progenitors capable of yielding...

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Autori principali: Phillips, M. Joseph, Perez, Enio T., Martin, Jessica M., Reshel, Samantha T., Wallace, Kyle A., Capowski, Elizabeth E., Singh, Ruchira, Wright, Lynda S., Clark, Eric M., Barney, Patrick M., Stewart, Ron, Dickerson, Sarah J., Miller, Michael J., Percin, E. Ferda, Thomson, James A., Gamm, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037340/
https://ncbi.nlm.nih.gov/pubmed/24532057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1667
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