PROFOUND REDUCTION OF OVARIAN ESTROGEN BY AROMATASE INHIBITION IN OBESE WOMEN

OBJECTIVE: We hypothesized that aromatase inhibitor (AI)-induced interruption of estradiol negative feedback would modulate the reproductive hormone profile of obese women. DESIGN AND METHODS: Regularly cycling women aged 18–40 with a BMI of 18–25kg/m2 (normal weight, n=10) or >30kg/m2 (obese; n=...

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Main Authors: Ross, Lauren A, Polotsky, Alex J, Kucherov, Alexander, Bradford, Andrew P., Lesh, Jennifer, Chosich, Justin, Gee, Nancy, Santoro, Nanette
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037337/
https://ncbi.nlm.nih.gov/pubmed/24482405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.20713
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