A Sensitive Method for Detecting Variation in Copy Numbers of Duplicated Genes

Gene duplications are common in the vertebrate genome, and duplicated loci often show a variation in copy number that may have important phenotypic effects. Here we describe a powerful method for quantification of duplicated copies based on pyrosequencing. A reliable quantification was obtained by a...

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Bibliographic Details
Main Authors: Pielberg, Gerli, Day, Andy E., Plastow, Graham S., Andersson, Leif
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2003
Subjects:
Methods
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC403722/
https://ncbi.nlm.nih.gov/pubmed/12952884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1188203
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