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A Sensitive Method for Detecting Variation in Copy Numbers of Duplicated Genes
Gene duplications are common in the vertebrate genome, and duplicated loci often show a variation in copy number that may have important phenotypic effects. Here we describe a powerful method for quantification of duplicated copies based on pyrosequencing. A reliable quantification was obtained by a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC403722/ https://ncbi.nlm.nih.gov/pubmed/12952884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1188203 |
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