Speech Sound Processing Deficits and Training-Induced Neural Plasticity in Rats with Dyslexia Gene Knockdown

In utero RNAi of the dyslexia-associated gene Kiaa0319 in rats (KIA-) degrades cortical responses to speech sounds and increases trial-by-trial variability in onset latency. We tested the hypothesis that KIA- rats would be impaired at speech sound discrimination. KIA- rats needed twice as much train...

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Main Authors: Centanni, Tracy M., Chen, Fuyi, Booker, Anne M., Engineer, Crystal T., Sloan, Andrew M., Rennaker, Robert L., LoTurco, Joseph J., Kilgard, Michael P.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037188/
https://ncbi.nlm.nih.gov/pubmed/24871331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098439
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