Adenoviral Vectors Expressing siRNAs for Discovery and Validation of Gene Function

RNA interference is a powerful tool for studying gene function and for drug target discovery in diverse organisms and cell types. In mammalian systems, small interfering RNAs (siRNAs), or DNA plasmids expressing these siRNAs, have been used to down-modulate gene expression. However, inefficient tran...

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Detalhes bibliográficos
Main Authors: Arts, Gert-Jan, Langemeijer, Ellen, Tissingh, Rudi, Ma, Libin, Pavliska, Heidi, Dokic, Kristina, Dooijes, Richele, Mešić, Emir, Clasen, Remko, Michiels, Frits, van der Schueren, Jan, Lambrecht, Mark, Herman, Sofie, Brys, Reginald, Thys, Kim, Hoffmann, Marcel, Tomme, Peter, van Es, Helmuth
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Methods
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC403715/
https://ncbi.nlm.nih.gov/pubmed/12975310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1332603
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