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Yeast artificial chromosome contigs reveal that distal variable-region genes reside at least 3 megabases from the joining regions in the murine immunoglobulin kappa locus.

The immunoglobulin kappa gene locus encodes 95% of the light chains of murine antibody molecules and is thought to contain up to 300 variable (V kappa)-region genes generally considered to comprise 20 families. To delineate the locus we have isolated 29 yeast artificial chromosome genomic clones tha...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: George, J B, Li, S, Garrard, W T
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40369/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8618913/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.26.12421
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