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Phospholipase D2 Enhances Epidermal Growth Factor-Induced Akt Activation in EL4 Lymphoma Cells

Phospholipase D2 (PLD2) generates phosphatidic acid through hydrolysis of phosphatidylcholine. PLD2 has been shown to play a role in enhancing tumorigenesis. The epidermal growth factor receptor (EGFR) can both activate and interact with PLD2. Murine lymphoma EL4 cells lacking endogenous PLD2 presen...

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Bibliografski detalji
Glavni autori: Chahal, Manpreet S., Brauner, Daniel J., Meier, Kathryn E.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036664/
https://ncbi.nlm.nih.gov/pubmed/27713341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph3072045
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