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Hydrophilic Modifications of an Amphiphilic Polynorbornene and the Effects on its Hemolytic and Antibacterial Activity

Here, we report the modification of an amphiphilic antibacterial polynorbornene, Poly3, via incorporation of hydrophilic, biocompatible groups. The sugar, zwitterionic, and polyethylene glycol based moieties were incorporated in varying ratios by copolymerization and post-polymerization techniques....

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Detalhes bibliográficos
Main Authors: Colak, Semra, Nelson, Christopher F., Nüsslein, Klaus, Tew, Gregory N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036528/
https://ncbi.nlm.nih.gov/pubmed/19138065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm801129y
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