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Defective Craniofacial Development and Brain Function in a Mouse Model for Depletion of Intracellular Inositol Synthesis

myo-Inositol is an essential biomolecule that is synthesized by myo-inositol monophosphatase (IMPase) from inositol monophosphate species. The enzymatic activity of IMPase is inhibited by lithium, a drug used for the treatment of mood swings seen in bipolar disorder. Therefore, myo-inositol is thoug...

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Main Authors: Ohnishi, Tetsuo, Murata, Takuya, Watanabe, Akiko, Hida, Akiko, Ohba, Hisako, Iwayama, Yoshimi, Mishima, Kazuo, Gondo, Yoichi, Yoshikawa, Takeo
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036449/
https://ncbi.nlm.nih.gov/pubmed/24554717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.536706
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