Hydroxycarbamide Decreases Sickle Reticulocyte Adhesion to Resting Endothelium by Inhibiting Endothelial Lutheran/Basal Cell Adhesion Molecule (Lu/BCAM) through Phosphodiesterase 4A Activation

Vaso-occlusive crises are the main acute complication in sickle cell disease. They are initiated by abnormal adhesion of circulating blood cells to vascular endothelium of the microcirculation. Several interactions involving an intricate network of adhesion molecules have been described between sick...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Chaar, Vicky, Laurance, Sandrine, Lapoumeroulie, Claudine, Cochet, Sylvie, De Grandis, Maria, Colin, Yves, Elion, Jacques, Le Van Kim, Caroline, El Nemer, Wassim
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036286/
https://ncbi.nlm.nih.gov/pubmed/24616094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.506121
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars