Specificity Protein 1 (Sp1) Maintains Basal Epithelial Expression of the miR-200 Family: IMPLICATIONS FOR EPITHELIAL-MESENCHYMAL TRANSITION

Epithelial-mesenchymal transition (EMT) is required for the specification of tissues during embryonic development and is recapitulated during the metastatic progression of tumors. The miR-200 family plays a critical role in enforcing the epithelial state with their expression lost in cells undergoin...

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Hlavní autoři: Kolesnikoff, Natasha, Attema, Joanne L., Roslan, Suraya, Bert, Andrew G., Schwarz, Quenten P., Gregory, Philip A., Goodall, Gregory J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036258/
https://ncbi.nlm.nih.gov/pubmed/24627491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.529172
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