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Glucose Transporter 8 (GLUT8) Mediates Fructose-induced de Novo Lipogenesis and Macrosteatosis

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in the world, and it is thought to be the hepatic manifestation of the metabolic syndrome. Excess dietary fructose causes both metabolic syndrome and NAFLD in rodents and humans, but the pathogenic mechanisms of fructose-indu...

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Autores principales: DeBosch, Brian J., Chen, Zhouji, Saben, Jessica L., Finck, Brian N., Moley, Kelle H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036240/
https://ncbi.nlm.nih.gov/pubmed/24519932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.527002
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