DNA Promoter Methylation-dependent Transcription of the Double C2-like Domain β (DOC2B) Gene Regulates Tumor Growth in Human Cervical Cancer

Double C2-like domain β (DOC2B) gene encodes for a calcium-binding protein, which is involved in neurotransmitter release, sorting, and exocytosis. We have identified the promoter region of the DOC2B gene as hypermethylated in pre-malignant, malignant cervical tissues, and cervical cancer cell lines...

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Detalhes bibliográficos
Main Authors: Kabekkodu, Shama Prasada, Bhat, Samatha, Radhakrishnan, Raghu, Aithal, Abhijit, Mascarenhas, Roshan, Pandey, Deeksha, Rai, Lavanya, Kushtagi, Pralhad, Mundyat, Gopinath Puthiya, Satyamoorthy, Kapaettu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036182/
https://ncbi.nlm.nih.gov/pubmed/24570007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.491506
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