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Structural Basis for Inactivation of Giardia lamblia Carbamate Kinase by Disulfiram
Carbamate kinase from Giardia lamblia is an essential enzyme for the survival of the organism. The enzyme catalyzes the final step in the arginine dihydrolase pathway converting ADP and carbamoyl phosphate to ATP and carbamate. We previously reported that disulfiram, a drug used to treat chronic alc...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4036171/ https://ncbi.nlm.nih.gov/pubmed/24558036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.553123 |
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