Neuroendocrine Signaling Via the Serotonin Transporter Regulates Clearance of Apoptotic Cells

Serotonin (5-hydroxytryptamine; 5-HT) is a CNS neurotransmitter increasingly recognized to exert immunomodulatory effects outside the CNS that contribute to the pathogenesis of autoimmune and chronic inflammatory diseases. 5-HT signals to activate the RhoA/Rho kinase (ROCK) pathway, a pathway known...

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Hlavní autoři: Tanaka, Takeshi, Doe, Jenna M., Horstmann, Sarah A., Ahmad, Shama, Ahmad, Aftab, Min, Sung-Joon, Reynolds, Paul R., Suram, Saritha, Gaydos, Jeanette, Burnham, Ellen L., Vandivier, R. William
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036168/
https://ncbi.nlm.nih.gov/pubmed/24570000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.482299
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