Disulfide Linkage and Structure of Highly Stable Yeast-derived Virus-like Particles of Murine Polyomavirus

VP1 is the major coat protein of murine polyomavirus and forms virus-like particles (VLPs) in vitro. VLPs consist of 72 pentameric VP1 subunits held together by a terminal clamp structure that is further stabilized by disulfide bonds and chelation of calcium ions. Yeast-derived VLPs (yVLPs) assemble...

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Bibliographic Details
Main Authors: Simon, Claudia, Klose, Thomas, Herbst, Sabine, Han, Bong Gyoon, Sinz, Andrea, Glaeser, Robert M., Stubbs, Milton T., Lilie, Hauke
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036163/
https://ncbi.nlm.nih.gov/pubmed/24567335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.484162
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