The Presence of Multiple Cellular Defects Associated with a Novel G50E Iron-Sulfur Cluster Scaffold Protein (ISCU) Mutation Leads to Development of Mitochondrial Myopathy

Iron-sulfur (Fe-S) clusters are versatile cofactors involved in regulating multiple physiological activities, including energy generation through cellular respiration. Initially, the Fe-S clusters are assembled on a conserved scaffold protein, iron-sulfur cluster scaffold protein (ISCU), in coordina...

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Detalhes bibliográficos
Principais autores: Saha, Prasenjit Prasad, Kumar, S. K. Praveen, Srivastava, Shubhi, Sinha, Devanjan, Pareek, Gautam, D'Silva, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036159/
https://ncbi.nlm.nih.gov/pubmed/24573684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.526665
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