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Regulation of Ku-DNA Association by Yku70 C-terminal Tail and SUMO Modification

The Ku70-Ku80 ring complex encloses DNA ends to facilitate telomere maintenance and DNA break repair. Many studies focus on the ring-forming regions of subunits Ku70 and Ku80. Less is known about the Ku70 C-terminal tail, which lies outside the ring. Our results suggest that this region is responsib...

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Detalhes bibliográficos
Main Authors: Hang, Lisa E., Lopez, Christopher R., Liu, Xianpeng, Williams, Jaime M., Chung, Inn, Wei, Lei, Bertuch, Alison A., Zhao, Xiaolan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036155/
https://ncbi.nlm.nih.gov/pubmed/24567323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.526178
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