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Mobile elements drive recombination hotspots in the core genome of Staphylococcus aureus

Horizontal gene transfer is an important driver of bacterial evolution, but genetic exchange in the core genome of clonal species, including the major pathogen Staphylococcus aureus, is incompletely understood. Here we reveal widespread homologous recombination in S. aureus at the species level, in...

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Autori principali: Everitt, Richard G., Didelot, Xavier, Batty, Elizabeth M., Miller, Ruth R, Knox, Kyle, Young, Bernadette C., Bowden, Rory, Auton, Adam, Votintseva, Antonina, Larner-Svensson, Hanna, Charlesworth, Jane, Golubchik, Tanya, Ip, Camilla L. C., Godwin, Heather, Fung, Rowena, Peto, Tim E. A., Walker, A. Sarah, Crook, Derrick W., Wilson, Daniel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Pub. Group 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036114/
https://ncbi.nlm.nih.gov/pubmed/24853639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4956
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