Methylation protects microRNAs from an AGO1-associated activity that uridylates 5′ RNA fragments generated by AGO1 cleavage

In plants, methylation catalyzed by HEN1 (small RNA methyl transferase) prevents microRNAs (miRNAs) from degradation triggered by uridylation. How methylation antagonizes uridylation of miRNAs in vivo is not well understood. In addition, 5′ RNA fragments (5′ fragments) produced by miRNA-mediated RNA...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ren, Guodong, Xie, Meng, Zhang, Shuxin, Vinovskis, Carissa, Chen, Xuemei, Yu, Bin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2014
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035956/
https://ncbi.nlm.nih.gov/pubmed/24733911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405083111
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