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Transformation of the cerebellum into more ventral brainstem fates causes cerebellar agenesis in the absence of Ptf1a function

Model organism studies have demonstrated that cell fate specification decisions play an important role in normal brain development. Their role in human neurodevelopmental disorders, however, is poorly understood, with very few examples described. The cerebellum is an excellent system to study mechan...

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Detalles Bibliográficos
Main Authors: Millen, Kathleen J., Steshina, Ekaterina Y., Iskusnykh, Igor Y., Chizhikov, Victor V.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035921/
https://ncbi.nlm.nih.gov/pubmed/24733890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315024111
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