The effect of the NMDA channel blocker memantine on salicylate-induced tinnitus in rats

Short-term tinnitus develops shortly after the administration of a high dose of salicylate. Since salicylate selectively potentiates N-methyl- D-aspartate (NMDA) currents in spiral ganglion neurons, it may play a vital role in tinnitus by amplifying NMDA-mediated neurotransmission. The aim of this s...

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Hlavní autoři: RALLI, M., TROIANI, D., PODDA, M.V., PACIELLO, F., ERAMO, S.L.M., DE CORSO, E., SALVI, R., PALUDETTI, G., FETONI, A.R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Pacini Editore SpA 2014
Témata:
Basic Research in Otolaryngology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035835/
https://ncbi.nlm.nih.gov/pubmed/24882929
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