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P53/microRNA-34-induced metabolic regulation: new opportunities in anticancer therapy

MicroRNA-34 (miR-34) is directly regulated by p53, and its potential tumor suppressive roles have been studied extensively. As a p53-induced microRNA, miR-34 functions as a tumor suppressor by playing a role in cell cycle arrest, apoptosis and metabolic regulation. Among these p53/miR-34 associated...

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Detalhes bibliográficos
Main Authors: Zhang, Ding-Guo, Zheng, Jun-Nian, Pei, Dong-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035797/
https://ncbi.nlm.nih.gov/pubmed/24884974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-115
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