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DPAGT1 myasthenia and myopathy: Genetic, phenotypic, and expression studies

OBJECTIVE: To investigate patients with DPAGT1 (UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase 1)-associated myasthenic syndrome. METHODS: We performed exome and Sanger sequencing, determined glycoprotein expression in patient muscles, assessed pathogenicity of the...

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Autores principales: Selcen, Duygu, Shen, Xin-Ming, Brengman, Joan, Li, Ying, Stans, Anthony A., Wieben, Eric, Engel, Andrew G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Lippincott Williams & Wilkins 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035711/
https://ncbi.nlm.nih.gov/pubmed/24759841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000435
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