Differential regulation of DNA methylation versus histone acetylation in cardiomyocytes during HHcy in vitro and in vivo: an epigenetic mechanism

The mechanisms of homocysteine-mediated cardiac threats are poorly understood. Homocysteine, being the precursor to S-adenosyl methionine (a methyl donor) through methionine, is indirectly involved in methylation phenomena for DNA, RNA, and protein. We reported previously that cardiac-specific delet...

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Main Authors: Chaturvedi, Pankaj, Kalani, Anuradha, Givvimani, Srikanth, Kamat, Pradip Kumar, Familtseva, Anastasia, Tyagi, Suresh C.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2014
Teme:
Call for Papers: Epigenetics and Epigenomics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035660/
https://ncbi.nlm.nih.gov/pubmed/24495916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00168.2013
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