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Achieving High-Frequency Optical Control of Synaptic Transmission

The optogenetic tool channelrhodopsin-2 (ChR2) is widely used to excite neurons to study neural circuits. Previous optogenetic studies of synapses suggest that light-evoked synaptic responses often exhibit artificial synaptic depression, which has been attributed to either the inability of ChR2 to r...

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Autors principals: Jackman, Skyler L., Beneduce, Brandon M., Drew, Iain R., Regehr, Wade G.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035530/
https://ncbi.nlm.nih.gov/pubmed/24872574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4694-13.2014
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