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Cartilage Tissue Engineering Using Dermis Isolated Adult Stem Cells: The Use of Hypoxia during Expansion versus Chondrogenic Differentiation

Dermis isolated adult stem (DIAS) cells, a subpopulation of dermis cells capable of chondrogenic differentiation in the presence of cartilage extracellular matrix, are a promising source of autologous cells for tissue engineering. Hypoxia, through known mechanisms, has profound effects on in vitro c...

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Bibliografiske detaljer
Main Authors: Kalpakci, Kerem N., Brown, Wendy E., Hu, Jerry C., Athanasiou, Kyriacos A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035316/
https://ncbi.nlm.nih.gov/pubmed/24867063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098570
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