Role of direct estrogen receptor signaling in wear particle-induced osteolysis

Estrogen withdrawal following surgical ovariectomy was recently shown to mitigate particle-induced osteolysis in the murine calvarial model. Currently, we hypothesize that estrogen receptors (ERs) were involved in this paradoxical phenomenon. To test this hypothesis, we first evaluated polyethylene...

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Main Authors: Nich, Christophe, Rao, Allison J., Valladares, Roberto D., Li, Chenguang, Christman, Jane E., Antonios, Joseph K., Yao, Zhenyu, Zwingenberger, Stefan, Petite, Hervé, Hamadouche, Moussa, Goodman, Stuart B.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035303/
https://ncbi.nlm.nih.gov/pubmed/23113918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.10.030
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