Exceptional Evolutionary Divergence of Human Muscle and Brain Metabolomes Parallels Human Cognitive and Physical Uniqueness

Metabolite concentrations reflect the physiological states of tissues and cells. However, the role of metabolic changes in species evolution is currently unknown. Here, we present a study of metabolome evolution conducted in three brain regions and two non-neural tissues from humans, chimpanzees, ma...

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Detalhes bibliográficos
Main Authors: Bozek, Katarzyna, Wei, Yuning, Yan, Zheng, Liu, Xiling, Xiong, Jieyi, Sugimoto, Masahiro, Tomita, Masaru, Pääbo, Svante, Pieszek, Raik, Sherwood, Chet C., Hof, Patrick R., Ely, John J., Steinhauser, Dirk, Willmitzer, Lothar, Bangsbo, Jens, Hansson, Ola, Call, Josep, Giavalisco, Patrick, Khaitovich, Philipp
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035273/
https://ncbi.nlm.nih.gov/pubmed/24866127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001871
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