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Mesodiencephalic Dopaminergic Neuronal Differentiation Does Not Involve GLI2A-Mediated SHH-Signaling and Is under the Direct Influence of Canonical WNT Signaling

Sonic Hedgehog (SHH) and WNT proteins are key regulators in many developmental processes, like embryonic patterning and brain development. In the brain, SHH is expressed in a gradient starting in the floor plate (FP) progressing ventrally in the midbrain, where it is thought to be involved in the de...

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Hlavní autoři: Mesman, Simone, von Oerthel, Lars, Smidt, Marten P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035267/
https://ncbi.nlm.nih.gov/pubmed/24865218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097926
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