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Acyclic CB[n]-Type Molecular Containers: Effect of Solubilizing Group on their Function as Solubilizing Excipients

We report the synthesis and x-ray crystal structures of three acyclic CB[n]-type molecular containers (2a, 2h, 2f) that differ in the charge on their solubilizing groups (SO(3)(−), OH, NH(3)(+)). The x-ray crystal structures of compounds 2h and 2f reveal a self-folding of the ArOCH(2)CH(2)X wall int...

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Autores principales: Zhang, Ben, Zavalij, Peter Y., Isaacs, Lyle
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035228/
https://ncbi.nlm.nih.gov/pubmed/24595500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ob42603c
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