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Non-invasive assessment of retinal alterations in mouse models of infantile and juvenile neuronal ceroid lipofuscinosis by spectral domain optical coherence tomography

INTRODUCTION: The neuronal ceroid lipofuscinoses constitute a group of fatal inherited lysosomal storage diseases that manifest in profound neurodegeneration in the CNS. Visual impairment usually is an early symptom and selective degeneration of retinal neurons has been described in patients sufferi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Groh, Janos, Stadler, David, Buttmann, Mathias, Martini, Rudolf
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035096/
https://ncbi.nlm.nih.gov/pubmed/24887158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-2-54
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