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Identification of Metabolites from LC-EC Profiling: GC-MS and Re-Fractionation Provide Essential Information Orthogonal to LCMS/microNMR

HPLC-coulometric electrode-array detection (LC-EC) is a sensitive, quantitative and robust metabolomics profiling tool that complements the commonly used MS and NMR-based approaches. However, LC-EC provides little structural information. We recently demonstrated a workflow for the structural charact...

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Bibliographic Details
Main Authors: Gathungu, Rose M., Bird, Susan S., Sheldon, Diane P., Kautz, Roger, Vouros, Paul, Matson, Wayne R., Kristal, Bruce S.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034759/
https://ncbi.nlm.nih.gov/pubmed/24657819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2014.01.020
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