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Early Alteration of Retinal Neurons in Aipl1(−/−) Animals

PURPOSE. Mutations in the photoreceptor cell-specific gene encoding aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) lead to Leber congenital amaurosis (LCA4), retinitis pigmentosa, and cone–rod dystrophy. Gene therapy appears to be promising in the treatment for AIPL1-mediated vision lo...

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Главные авторы: Singh, Ratnesh Kumar, Kolandaivelu, Saravanan, Ramamurthy, Visvanathan
Формат: Artigo
Язык:Inglês
Опубликовано: The Association for Research in Vision and Ophthalmology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034756/
https://ncbi.nlm.nih.gov/pubmed/24736053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-13728
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