No evidence that runs of homozygosity are associated with schizophrenia in an Irish genome-wide association dataset

Runs of homozygosity (ROH), regions of the genome containing many consecutive homozygous SNPs, may represent two copies of a haplotype inherited from a common ancestor. A rare variant on this haplotype could thus be present in a homozygous and potentially recessive state. To detect rare risk variant...

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Détails bibliographiques
Auteurs principaux: Heron, Elizabeth A., Cormican, Paul, Donohoe, Gary, O’Neill, Francis A., Kendler, Kenneth S., Riley, Brien P., Gill, Michael, Corvin, Aiden P., Morris, Derek W.
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034753/
https://ncbi.nlm.nih.gov/pubmed/24560374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2014.01.038
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