Metformin and Prostate Cancer: Benefit for Development of Castration-resistant Disease and Prostate Cancer Mortality

BACKGROUND: In vitro data and early clinical results suggest that metformin has desirable antineoplastic effects and has a theoretical benefit on castration-resistant prostate cancer (CRPC). OBJECTIVE: To determine whether the use of metformin would be associated with improved clinical outcomes and...

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Bibliografiske detaljer
Main Authors: Spratt, Daniel E., Zhang, Chi, Zumsteg, Zachary S., Pei, Xin, Zhang, Zhigang, Zelefsky, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034673/
https://ncbi.nlm.nih.gov/pubmed/23287698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2012.12.004
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