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Obtaining Accurate P-values from a Dense SNP Linkage Scan
A major concern of resequencing studies is that the pathogenicity of most mutations is difficult to predict. To address this concern, linkage (i.e. co-segregation) is often used to exclude mutations, and to better predict pathogenicity among the candidate mutations that remain. However, when linkage...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4034466/ https://ncbi.nlm.nih.gov/pubmed/23038223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000342754 |
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