Microparticles from Stored Red Blood Cells Activate Neutrophils and Cause Lung Injury after Hemorrhage and Resuscitation

BACKGROUND: Transfusion of stored blood is associated with increased complications. Microparticles (MPs) are small vesicles released from RBCs that can induce cellular dysfunction, but the role of RBC-derived MPs in resuscitation from hemorrhagic shock is unknown. In the current study, we examined t...

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Detalhes bibliográficos
Main Authors: Belizaire, Ritha M, Prakash, Priya S, Richter, Jillian R, Robinson, Bryce R, Edwards, Michael J, Caldwell, Charles C, Lentsch, Alex B, Pritts, Timothy A
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034387/
https://ncbi.nlm.nih.gov/pubmed/22342784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jamcollsurg.2011.12.032
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